PARNWAD MUNJIT, M.D.
Gastroenterology and Hepotology

Daily behavior, or what we call each individual's lifestyle, plays a highly critical role in the development of esophageal ulcers. Habits such as preferring extremely spicy foods, pickled foods, snacks, greasy foods, and very sweet desserts can increase gas production in the stomach. When this gas builds up, it has a high chance of overflowing, causing stomach acid or digestive enzymes to reflux into the esophagus. This leads to irritation and ulcers, subsequently causing symptoms like difficulty swallowing, painful swallowing, or a sensation of fullness and tightness in the throat or chest area.
The food we eat must pass through the esophagus down into the stomach. The esophagus is an organ connecting the oral cavity to the stomach, shaped like a short, round tube. Its primary function is to transport food to the stomach; it does not digest food. The esophagus contracts and relaxes in rhythmic, successive intervals and can squeeze shut to prevent food in the stomach from refluxing back up—an issue that is a major cause of esophageal ulcers.
Other causes include certain types of medications, which can also trigger ulcers in the esophagus. Additionally, bacterial, fungal, or viral infections can be a source of esophageal ulceration.
Consuming highly acidic foods and beverages—such as sour fruits, tea, coffee, or alcoholic drinks—can lead to adverse consequences. If consumed in excess, they can directly irritate and damage the esophageal lining. Another crucial factor is medication; for instance, taking certain antibiotics or acne treatments and immediately lying down can cause the pill to get lodged and dissolve in the esophagus, leading to localized ulceration.

Symptoms vary widely, ranging from chest pain, heartburn, and sour burping to chest tightness. In severe cases, patients may experience difficulty swallowing or painful swallowing, which can lead to coughing, choking, or even asthma-like symptoms in some individuals. Furthermore, esophageal ulcers are often accompanied by gastritis and esophagitis, which increase stomach acid production and weaken the lower esophageal sphincter's ability to contract. This combination leads to even more acid reflux, exacerbating the ulcers in the esophagus.

If esophageal ulcers are left inflamed and untreated chronically over a long period, a small ulcer can gradually expand. Fast-spreading cellular changes can occur, causing the localized cells to become abnormal and undergo dysplastic changes, potentially developing into cancer. Most patients eventually present with difficulty or pain when swallowing, chest pain, a lump-like sensation in the throat, or choking while eating. Once patients cannot eat and begin choking, it leads to weight loss, malnutrition, emaciation, and ultimately, esophageal cancer.
Esophageal ulcers have a very high chance of being completely cured if diagnosed and treated early. Modern medical technology allows for highly precise diagnostic methods, including:
Particularly, therapeutic upper GI endoscopy allows doctors to perform esophageal dilation (similar to balloon angioplasty) to widen a narrowed lumen. We can fully visualize the entire length and lining of the esophagus. If there is any suspicion of abnormal tissue or infection-related ulceration, a small tissue sample (biopsy) can be taken immediately for pathological analysis, while treating complications concurrently.
However, the primary treatment remains medication, and modern drugs are highly effective—especially proton pump inhibitors (acid reducers). If taken consistently and correctly for the prescribed duration, the esophageal ulcer can heal completely. On the contrary, stopping the medication early or taking it irregularly significantly increases the likelihood of recurrence.
If esophageal ulcers are left inflamed and untreated chronically over a long period, a small ulcer can gradually expand. Fast-spreading cellular changes can occur, causing the localized cells to become abnormal and undergo dysplastic changes, potentially developing into cancer.